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I’ m sure all of us ever consumed antibiotics, but how to get or to prescribed rational antibiotics ? Prophylactic antibiotics are used to prevent infection from contamination of a wound. They should not begiven to prevent other postoperative infections (e.g.chest infection).

Audit has shown that, not only are the wrong antibiotics often chosen, but, more importantly, the timing is often incorrect. Case–control studies have failed to show conclusively that one antibiotic is superior for prophylaxis. The choice of antibiotic depends on the likely pathogens that occur at various sites. Antibiotics should be given intravenously at induction of anaesthetic to facilitate high concentrations in the operation site at the time when contamination occurs. A number of well-controlled trials have advised single-dose prophylaxis over multiple doses.

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